Aldevron Breakthrough Blog
Presentation: Innovative RNA Manufacturing
January 22, 2025 by Aldevron
Breaking Barriers with Mutant T7 Polymerase
For mRNA manufacturing, especially if you are working sequence-to-vial, ensuring that a service provider has the proper capabilities is critical to project success. Aldevron has expanded its end-to-end mRNA services to meet those needs and show its commitment to accelerating mRNA research and development, expanding its capabilities to streamline the entire mRNA manufacturing process.
In his talk, Innovative RNA Manufacturing: Breaking Barriers with Mutant T7 Polymerase, presented at the mRNA Process Development & Manufacturing Summit, Aldevron Senior Director of Product Management Nate Spangler discussed several key advancements in the field:
- Optimized RNA Synthesis: Leveraging the power of Codex® HiCap T7 RNAP to improve mRNA quality and yield.
- Advanced LNP Encapsulation: Partnering with industry leaders to enable robust and scalable LNP manufacturing.
- Enhanced Analytical Services: Providing comprehensive analytical solutions to support rigorous quality control and regulatory compliance.
By addressing critical challenges in mRNA manufacturing, Aldevron is helping researchers bring innovative therapies to market faster. You can learn more about the manufacturing process in his presentation, available below.
View Innovative RNA Manufacturing: Breaking Barriers with Mutant T7 Polymerase
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Aldevron serves the biotechnology industry with custom production of nucleic acids and proteins. Thousands of clients use Aldevron-produced plasmids, RNA and gene editing enzymes for projects ranging from research grade to clinical trials to commercial applications. Aldevron specializes in cGMP manufacturing and is known for inventing the GMP-Source® quality system. Aldevron operates the largest cGMP plasmid DNA manufacturing facility in the world at company headquarters in Fargo, North Dakota, with additional facilities in Madison, Wisconsin.