Aldevron Breakthrough Blog
Webinar On Demand: Revolutionizing mRNA Manufacturing
April 2, 2025 by Aldevron
Introducing AlchemyTM Cell-free DNA Technology
Time. It’s an overriding element therapeutics developers and manufacturers face in the production process. Enter Aldevron’s new Alchemy™ Cell-free DNA technology. In an Outsourced Pharma Capacity Update (OPCU) webinar, Nate Russart, PhD, and Tanner Dockendorf discussed the advantages of Alchemy, a next-generation solution for rapid production of linear DNA template for mRNA manufacturing. This innovative synthetic technology can cut production timelines by over 50%.
In this presentation, Russart and Dockendorf show how Alchemy technology utilizes a cell-free, enzymatic DNA manufacturing process that accelerates linDNA template production, allowing you to expedite your mRNA pipeline. The key highlights of the discussion on Alchemy’s advantages include:
- Accelerated Production: Reduces linDNA template production timelines by half, enabling faster mRNA synthesis.
- Enhanced Purity: Eliminates bacterial cells from the amplification process, resulting in cleaner linear DNA templates free from host cell contaminants.
- Industry-leading Efficiency: Produces high-quality linear DNA templates swiftly and reliably.
- Comparable Activity: Comparable to traditional linear plasmid DNA templates, ensuring consistency and reliability in mRNA production.
This presentation is available on demand for you to learn more about Alchemy and what it might offer you as we move into the future of mRNA production and offer the means to transform your manufacturing processes.
- Have questions about this topic? Contact Us
- Visit our Alchemy Cell-free DNA Technology web page
- Have an idea for a topic? Let us know!
Aldevron serves the biotechnology industry with custom production of nucleic acids and proteins. Thousands of clients use Aldevron-produced plasmids, RNA and gene editing enzymes for projects ranging from research grade to clinical trials to commercial applications. Aldevron specializes in cGMP manufacturing and is known for inventing the GMP-Source® quality system. Aldevron operates the largest cGMP plasmid DNA manufacturing facility in the world at company headquarters in Fargo, North Dakota, with additional facilities in Madison, Wisconsin.