RNA Cloning Backbones

Optimized RNA Backbones for Enhanced Vaccine and Therapeutic Development

Aldevron's backbone options are designed to enhance mRNA production, making them highly suitable for developing vaccines and therapeutics. Our various constructs feature a T7 promoter for RNA production, and options with encoded poly(a) region and proprietary 5’ UTR sequence.

Key Features of our Proprietary 5’ UTR mRNA Backbones include

Unique UTR Sequences

We offer two options with different UTR sequences which allows researchers to determine which UTR configuration works best for RNA stability and translation efficiency in your specific application.

No License Fee

These backbones are available without licensing fees. This can significantly reduce the financial burden on researchers and companies developing RNA-based products.

Ideal for RNA Development

Optimized for efficient product of high-quality RNA, these backbones are perfect for developing various RNA-based applications, including vaccines and therapies.

Flexible and Ready to Use

The flexible and ready to use backbones allow researchers to quickly integrate these 5’ UTR sequences into your mRNA manufacturing workflows.

Practical Applications

• RNA Vaccines: The optimized backbones can be used to produce high-quality mRNA for vaccines, ensuring robust immune responses and effective protection against diseases.
• RNA Therapies: For therapeutic applications, the stability and efficiency provided by these backbones can enhance the delivery and efficacy of RNA-based treatments.

By leveraging Aldevron's proprietary backbones, you can streamline their RNA production processes, reduce costs, and improve the quality and effectiveness of their RNA vaccines and therapies.