Research Grade mRNA Production with Codex® HiCap Polymerase
Optimize mRNA production from the very start
Aldevron’s Research Grade RNA manufacturing is now utilizing Codex® HiCap as the standard to deliver top quality mRNA with no additional costs
As mRNA programs develop, quantity and quality requirements increase. Starting with production at the research grade phase, pure mRNA minimizes unwanted immunogenicity, allowing smoother program progression.
Our research grade mRNA services with Codex® HiCap Polymerase offers scalability, raw material and process controls, raw material cost control, and RG-to-cGMP transferability, ensuring consistent quality and affordability.
Using Codex® HiCap enzyme in our research grade mRNA production generates fewer undesirable dsRNA byproducts than WT T7 RNA polymerase, reducing unwanted immunogenicity and efficiently incorporating commercially available cap analogs. The result is a superior production of pure RNA for our clients at no additional cost.
mRNA synthesis enzymes
Utilizing our in-house in vitro transcription and capping enzymes, we custom manufacture your research grade mRNA with our NEW Codex® HiCap T7 RNA Polymerase. It is a co-transcriptional capping RNA polymerase engineered to produce synthetic RNA to meet increasing demands for safety and cost-effectiveness.
Codex® HiCap T7 RNA Polymerase:
- Reduces immunogenic double-stranded RNA (dsRNA) by-products
- Requires up to 62% less cap analog to achieve >95% capping efficiency
- Retained RNA yield and integrity
Codex® HiCap RNA Polymerase Resources
- RNA Full Services Brochure
- Codex® HiCap RNA Polymerase Brochure
- Poster: HiCap T7 transcribes RNA with higher purity and activity while using less cap analog
- Webinar: Streamlining the Path from Discovery to Patient
Improve your mRNA manufacturing with the essential starting material. Partner with us today!
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