Webinar: Mastering mRNA Manufacturing - Unlocking Process Development for Clinical Success

Watch Our Exclusive Webinar!

Are you ready to delve into the complexities of process development for successful clinical grade mRNA manufacturing? Join us for an insightful and in-depth webinar featuring industry experts Nathan Lee, Senior Director of CMC at Poseida Therapeutics, and Venkata Indurthi, Chief Scientific Officer at Aldevron. This session is your ultimate guide to mastering the intricacies of mRNA process development, ensuring the production of high-quality mRNA suitable for clinical applications.

Webinar Highlights

• Understanding mRNA: Gain a comprehensive overview of the essential components of mRNA and self-amplifying RNA (saRNA), and learn why process development is crucial for clinical success.
• Manufacturing Challenges and Solutions: Discover the inherent complexities of mRNA manufacturing and explore key decisions in the capping and tailing processes that impact mRNA quality and yield.
• Process Development Considerations: Learn about the five critical areas of process development, including purity, impurities, critical process parameters, modified nucleotides, and capping technology.
• Detailed Case Studies: Dive deep into real-world examples of process development strategies with case studies on self-amplifying RNA with enzymatic capping and mRNA with co-transcriptional capping and enzymatic tailing.
• Q&A Session: Learn from the questions answered by our experts during the interactive Q&A segment.

Key Insights:

Process development is the backbone of clinical-grade mRNA manufacturing, ensuring that the end product meets the stringent quality and safety standards necessary for clinical applications. This webinar will equip you with the knowledge and insights needed to:

• Achieve consistency and reliability in mRNA production.
• Optimize yield and purity for high-quality mRNA.
• Scale up from laboratory to clinical manufacturing efficiently.
• Develop cost-effective manufacturing processes.
• Ensure regulatory compliance for clinical applications.

Meet the Speakers

Nathan Lee, Senior Director of CMC at Poseida Therapeutics

Nathan brings extensive experience in clinical-stage advanced therapeutics, specializing in DNA delivery systems and gene editing. His expertise in process development and manufacturing has been instrumental in advancing Poseida's differentiated non-viral therapeutics.

Venkata Indurthi, Chief Scientific Officer at Aldevron

Venkata leads scientific and technical research at Aldevron, focusing on nucleic acid production. With a deep understanding of mRNA manufacturing, Venkata has driven significant advancements in optimizing process development to ensure high-quality mRNA production.

Learn how Aldevron can support mRNA programs for clinical success. Watch our webinar today!