In-Stock GMP Plasmid DNA Supporting Lentiviral & AAV Vector Programs

pALD-Lenti System

Aldevron provides pALD Lenti packaging plasmids through our partnership with OXGENE, who have optimized them for lentiviral vector production. They are immediately available at all quality levels, eliminating the need to manufacture custom batches. This reduces your costs and significantly reduces time to manufacture vectors for clinical trials.

• Immediately available at Research Grade and GMP-Source®
• Royalty free
• Demonstrated performance producing high-quality lentiviral vectors

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pALD-AAV System

Recombinant AAV (rAAV) manufacturing is composed of four main components which include a rep/cap plasmid, a helper plasmid, a transgene plasmid, and a viral packaging cell line. Triple transfection of the three plasmids into HEK293 cells is the most frequently used rAAV production method.

• Royalty free, including for commercial products
• Kanamycin resistance
• Consistent, reliable supply
• Immediately available at research grade

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pALD-X80 Helper Plasmid

Triple transfection is the most common method for rAAV production and does not require co-infection with adenovirus; a helper plasmid provides adenoviral genes. Aldevron's pALD-X80 has several advantages.

• Immediately available at research, GMP-Source® and cGMP
• Royalty free, including for commercial products
• Replaces any rAAV helper plasmid
• Kanamycin resistance
• Consistent, reliable supply

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